Roland Topor wrote the novel The Tenant (Le Locataire chimérique, 1964), which was adapted to film by Roman Polanski in 1976. The Tenant is the story of a Parisian of Polish descent, a chilling exploration of alienation and identity, asking disturbing questions about how we define ourselves. The later novel Joko's Anniversary (1969), another fable about loss of identity, is a vicious satire on social conformity.

A new presentation of The Tenant by Roland Topor was released in October, 2006. The book has Topor's original novel, a new introduction by Thomas Ligotti, a selection of short stories by Topor, a representation of Topor's artwork and an essay on the famous Roman Polanski film version. There is a working possibility of having Mr. Polanski write a new foreword to this edition.

Thomas Ligotti's introduction clocks in at 3500 words and concerns the affirmative themes of world-renowned authors, focusing on Luigi Pirandello, with the negationist themes of Roland Topor's The Tenant.

Roland Topor wrote two songs for Megumi Satsu, "Je m'aime" and "Monte dans mon Ambulance"

With René Laloux, Topor made "The Dead Times" ("Les Temps morts", 1964), "The Snails" ("Les Escargots", 1965) and their most famous work, the feature length La Planète Sauvage (1973).

Topor also worked as an actor, his most famous part being Renfield in Werner Herzog's Nosferatu: Phantom der Nacht (1979).

Topor published several books of drawings, including Dessins panique (1965) Quatre roses pour Lucienne (1967) and Toporland (1975). Selections from Quatre roses pour Lucienne were reprinted in the English language collection Stories and Drawings (1967). His carefully detailed, realistic style, with elaborate crosshatching, emphasises the fantastic and macabre subject matter of the images.

1962 - Creates the Panic Movement (mouvement panique), together with Alejandro Jodorowsky and Fernando Arrabal.

1961 to 1965 - Contributes to French satirical magazine Hara-Kiri.

1965 - Creates, with partner René Laloux, the animated short film "Les Escargots." The movie won Special Jury Prize at the Cracow Film Festival.